Course syllabus

Cellbiologi
Cell biology

KBK070, 7,5 credits, G2 (First Cycle)

Valid for: 2016/17
Decided by: Education Board C
Date of Decision: 2016-04-12

General Information

Main field: Technology.
Compulsory for: B3
Language of instruction: The course will be given in Swedish

Aim

The aim of the course is to give an understanding of basic molecular mechanisms in a living cell.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

be able to describe and explain:

- the structure of a eucaryotic cell and the cell cycle

- eucaryotic genes and their control

- stem cells, stem cell therapy and cell cloning

- structure and function of the human immune system

- basic physiological processes in the human body

Competences and skills
For a passing grade the student must

• be able to prepare a short, written report of a central area in cell biology based on individually identified scientific articles,
• be able to orally present a central area of cell biology,
• be able to prepare and isolate eucaryotic DNA.

Judgement and approach
For a passing grade the student must

• be able to perform basical ethical positions within cell biology,
• be able to do a basic assessment of the quality of scientific work in cell biology.

Contents

The cell nucleus and the organisation of the chromatin. Gene structure, exons and introns. Protein sorting and secretion. Cell division, mitosis, control of the cell cycle, meiosis. Immunology. Molecular physiology. Stem cells and cancer. Cultivation of higher eucaryotic cells. Ethical considerations.

Examination details

Grading scale: TH
Assessment: Written and oral report of an individual literature task. Written exam. Approved laboratory report is required.

Parts
Code: 0105. Name: Cell Biology, Theory.
Credits: 6. Grading scale: TH. Assessment: Written report of an individual literature task. Written examination. Contents: Molecular genetics of the cell. The cell nucleus and the organisation of the chromatin. Gene structure, exons and introns. Evolution of the genome. Flow of information in the cell. DNA replication, repair and genetic recombination. RNA and its roles, translation to proteins. Protein sorting and secretion. Cell division, mitosis, control of the cell cycle, meiosis. Functional genomics. Molecular physiology. Cultivation of higher eucaryotic cells.
Code: 0205. Name: Cell Biology, Practicals.
Credits: 1,5. Grading scale: UG. Assessment: Approved laboratory report. Contents: Purification of eucaryot DNA

Admission

Admission requirements:

• KBK011 Biochemistry

The number of participants is limited to: No
The course overlaps following course/s: KBK020

Reading list

• Berg, J.M. and Tymoczko, J.L., Stryer, L.: Biochemistry. W.H. Freeman & Co, 2011, ISBN: 978-1-4292-7635-1.
• Alberts, B., Johnsson, A., Lewis, J., Morgan, D. Raff, M: Molecular Biology of the Cell. Garland Publishing, 2014, ISBN: 9780815344643.
• Laborationskompendium i Cellbiologi. 2015.

Contact and other information

Course coordinator: Leif Bülow, Leif.Bulow@tbiokem.lth.se
Teacher: Cedric Dicko, Cedric.Dicko@tbiokem.lth.se
Teacher: Svetlana Leonova, Svetlana.Leonova@tbiokem.lth.se
Teacher: Lieselotte Cloetens, Lieselotte.Cloetens@tbiokem.lth.se
Course homepage: http://www.tbiokem.lth.se