Course syllabus

Drug Synthesis

KOK090, 7,5 credits, A (Second Cycle)

Valid for: 2012/13
Decided by: Education Board 2
Date of Decision: 2012-04-04

General Information

Elective for: B4-l, K4-m, K4-l
Language of instruction: The course will be given in English on demand


The aim of the course is to give advanced knowledge in synthetic organic chemistry and knowledge in physical organic chemistry.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

Competences and skills
For a passing grade the student must


The course deals primary with organic chemical reactions for the creation of C-C bonds emphasising enolate chemistry but also using pericyclic reactions and radical chemistry. The course also gives advanced knowledge in oxidation and reduction reactions in organic chemistry. The emphasis is on the different chemo-, regio- and diastereoselectivity of the different reaction types. Fundamental retrosynthetic analysis of target molecules is used as means to design multistep synthesis. The course is focused on applying a mechanistic approach to understand the outcome of chemical reactions and to emphasise this, the reactions are analyzed using basic frontier orbital analysis. A large part of the course treats methods to elucidate mechanisms of reactions such as linear free energy relationships and the primary isotope effect.

An important aspect of the course is to orally present organic reactions to other students. The role of organic chemistry and in material science will be presented.

Examination details

Grading scale: TH
Assessment: To pass the course you need to pass a written exam.


Admission requirements:

The number of participants is limited to: No
The course overlaps following course/s: KOK020, KOK021

Reading list

Contact and other information

Course coordinator: Universitetslektor Kenneth Wärnmark,
Course homepage:
Further information: Part of the course is given together with KEMM01, a course at the Science Faculty.