Course syllabus

Läkemedelsformulering och produktion
Drug Formulation and Production

KLGN60, 7,5 credits, A (Second Cycle)

Valid for: 2021/22
Faculty: Faculty of Engineering, LTH
Decided by: PLED B/K
Date of Decision: 2021-04-14

General Information

Main field: Pharmaceutical Technology.
Compulsory for: B4-l, K4-l, MLAK1
Elective for: N5-nbm
Language of instruction: The course will be given in English

Aim

The aim of this course is to give, based on basic knowledge of chemistry and chemical engineering give, a deepend understanding of formulation and production of pharmaceutical.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

Competences and skills
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Contents

The course describes pharmaceutical products and production with an emphasis on physicochemical and chemical engineering questions. It also describes what happens to the drug product in the living organism when administered through different routes. The course focuses on different pharmaceutrical formulations such as solutions, suspensions, emulsions, granulates, tablets, capsules, aerosols, creams etc.

Furthermore the course will give an overview of the quality aspects of pharmaceutical industry, and special requirements on pharmaceutical industry when it comes to demands from authorities both Swedish and international. The laboratory assignments will illustrate important formulation aspects and how to evaluate quality and physical chemical properties of the formulation. Furhtermore they will illustrate different quality documents in the industry.

Examination details

Grading scale: TH - (U,3,4,5) - (Fail, Three, Four, Five)
Assessment: Oral exam, active participation in case work and laborative work, written laboration reports according to industry and oral presentation of a project. Fina grade is based on the oral exam.

The examiner, in consultation with Disability Support Services, may deviate from the regular form of examination in order to provide a permanently disabled student with a form of examination equivalent to that of a student without a disability.

Parts
Code: 0120. Name: Drug Formulation Oral Exam and Assignments.
Credits: 4. Grading scale: TH. Assessment: Grade is judged on quality of answers to questions and complexity of the choosen questions as described in SOP for exam Contents: Oral exam on handed in questions before exam students needs to have passed assignments quizzes in Canvas
Code: 0220. Name: Project.
Credits: 2. Grading scale: UG. Assessment: active participation in project and discussions concerning the project Poster Two oral presentations A product specification Contents: A project where the students should describe a drug product based on an active substance and how to produce this. choose patient group and discusse ethical issues concerning the choices made.
Code: 0320. Name: Practical Assignment.
Credits: 1,5. Grading scale: UG. Assessment: Production master Plan and report for one laborative assignment Participate i seminar Contents: Two laborative assignments

Admission

Assumed prior knowledge: KFKF01 Molecular Driving Forces 2: Interactions and Dynamics
The number of participants is limited to: No
The course overlaps following course/s: KLG027, KLGN35

Reading list

Contact and other information

Course coordinator: Professor Marie Wahlgren, Marie.Wahlgren@food.lth.se
Course administrator: Liselotte Eriksson, liselotte.eriksson@food.lth.se
Course homepage: http://www.food.lth.se