Valid for: 2021/22
Faculty: Faculty of Engineering, LTH
Decided by: PLED BME
Date of Decision: 2021-04-14
Main field: Technology.
Compulsory for: BME3
Language of instruction: The course will be given in English on demand
The course will give the students insights into how biochemical and biomolecular diagnostics are utilised in today’s health care, in hospital laboratories as well as in primary health care and in-hospital care. The most common clinical chemical analyses and various public health issues are discussed. The principles for pharmacological therapy are illustrated, as well as the concepts of biobanking and different types of ”omics”. The most common latin/greek terms used in health care will be discussed. The course requires no prior knowledge in clinical chemistry and will to a large extent be based on patient case studies.
Knowledge and understanding
For a passing grade the student must
* Have knowledge of the most common disesases – prevalence, risk factors, progression and treatment.
* Have knowledge of the principles for and use of assisted fertilisation
* Have knowledge of the mechanisms of some common pharamacological substance groups.
* Have knowledge of the implication of the biobank legislation.
* Have knowledge of different ”omics” – concepts and their impact on diagnostics.
* Understand the greek/latin terms of common diseases and anatomy.
Competences and skills
For a passing grade the student must
* be able to create and follow a studyplan of the most common clinical chemical analyses - principles of analysis, indications and clinical relevance.
* be able to interpret the most common bed-side analyses - principles of analysis, indications and clinical relevance.
* be able to use the greek/latin terms of common diseases and anatomy.
The course content includes
* The most common clinical chemical analyses, indications, principles of analysis and interpretation – e.g. what is CRP, how is CRP measured and what a high level of CRP implies.
* Fundamental knowledge of the most common diseases - e.g. cardiovascular diseases, tumours and diabetes – prevalence , pathofysiology and implications; e.g. how common is diabetes, why do one get diabetes, which are the most common complications?
* The most common medical terms – e.g. myocardial infarction, hypertension, aortic rupture, anterior and distal.
* The principles of bedside diagnostics – which analyses are performed in primary health care and how are they used, advantages and drawbacks.
* The principles of assisted fertilisation – pathofysiological background to and clinical handling of infertlity.
* The mechanisms of some common pharamacological substance groups – e.g. drugs for the treatment of high blood pressure, diabetes, infections, cancer or pain such as betablockers, insuline, antibiotics, cytostatics and painkillers.
* The main features and application of the biobank legislation – what is a biobank, who can ”deposit” and ”withdraw”, who owns the samples?
* Different ”omics” – what is the meaning of genomics, proteomics, transcriptomics and metabolomics? How can the information be used in research and health care? Why does the genome and proteome of individuals differ?
Grading scale: UG - (U,G) - (Fail, Pass)
Assessment: During the course, two compulsory project work is carried out in groups which are presented in oral presentations. For an approved course, active participation in the project work and the laboratory sessions, approved laboratory reports and an approved written exam are required.
The examiner, in consultation with Disability Support Services, may deviate from the regular form of examination in order to provide a permanently disabled student with a form of examination equivalent to that of a student without a disability.