Valid for: 2016/17
Decided by: Education Board B
Date of Decision: 2016-03-29
Elective for: BME4-bf, D4, E4-mt, F4, F4-f, F4-mt, N4, Pi4
Language of instruction: The course will be given in English
The aim with the course is to give the student knowledge of the interaction between light and highly scattering media, such as e.g. tissue. This knowledge is central for a large number of clinical diagnostic tools as well as laser based treatment modalities. Biomedical optics is a fast developing field of research and the medical industry will require people with this knowledge in the near future.
Knowledge and understanding
For a passing grade the student must
be able to explain basic interactions between light and tissue
be able to explain how optical properties of highly scattering media can be measured
be able to describe how light propagation in tissue can be simulated
be able to in depth describe an example of use of optics/lasers ain biomedical applications
be able to briefly describe other therapeutic and diagnostic medical laser applications
be able to explain the basic principles for therapeutic and diagnostic applications of lasers in medicine
Competences and skills
For a passing grade the student must
be able to measure optical properties of tissue
be able to model light propagation in tissue
have gained competence in composing a report describing an accomplished project, with emphasis on a thorough analysis of published data and own results
be able to integrate and analyse information from multiple sources
Judgement and approach
For a passing grade the student must
be able to choose and motivate a modelling approach for light propagation in a turbid medium under specific conditions
be able to choose and motivate a suitable measurement technique to obtain optical properties of tissue depending on tissue type and condition, wavelength and geometry
be able to evaluate what the critical laser parameters are for a specific medical laser application
be able to find relevant information on the internet and in libraries
have gained an interest for challenges in biophotonics and medical laser applications, especially for problems related to light propagation in turbid media.
Medical applications of lasers. Theory: light propagation in strongly scattering media, analytical and numerical solution of diffusion equations, Monte Carlo simulations, heat transfer equations. Measurements of the properties of strongly diffusive media, temperature distribution in tissue following laser irradiation. Mathematical modelling of light and heat distribution in tissue.
Lectures: light transport in tissue, optical properties of tissue, laser based medical applications
Laboratory exercises: time-resolved spectroscopy and fluorescence imaging
Computer exercises: Diffusion theory, Monte-Carlo simulations and FemLab as a simulation tool
Grading scale: TH
Assessment: For grade 3 approved project and exercises are sufficient. The project is performed in groups of two students. The project is presented both orally and as a written report. For higher grades a written examination is required. A well performed project can give bonus points at the first regular examination. The project, two laboratory exercises and three computer exercises are compulsory.
Required prior knowledge: Knowledge of physics corresponding to a basic course in Physics at university level; Knowledge of mathematics equivalent to FMAF01 Mathematics - Analytic Functions and FMAF05 Mathematics - Systems and Transforms.
The number of participants is limited to: 40
Selection: Credits awarded or credited within the study programme.
Course coordinator: Stefan Andersson-Engels, stefan.andersson-engels@fysik.lth.se
Teacher: Johan Axelsson, johan.axelsson@fysik.lth.se
Course homepage: http://www.atomic.physics.lu.se/education/elective_courses/faf150_medical_optics/