Course syllabus

Läkemedelskemi
Medicinal Chemistry

KOKN01, 7,5 credits, A (Second Cycle)

Valid for: 2016/17
Decided by: Education Board C
Date of Decision: 2016-04-12

General Information

Compulsory for: B4-l, K4-l
Elective for: N4-nbm
Language of instruction: The course will be given in English on demand

Aim

The aim of the course is to give basic knowledge in and broad understanding of medicinal chemistry and pharmacological principles from a molecular perspective.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

Competences and skills
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Contents

The course discusses general pharmacological principles, drug development and presents various classes of drugs, their effects, their use, and chemical structures. Important parts of medicinal chemistry, such as drugs of the nerve system, hormone drugs, drugs affecting the heart, respiratory drugs, anaesthetics, sedative drugs, antivirals, antibiotics, and cancer drugs. Methods for searching novel drug candidates (drug development), development of computer models for prediction of various pharmacological properties, and structure-activity relationships are discussed.

Examination details

Grading scale: TH
Assessment: Written assessment.

Admission

Required prior knowledge: KOO101 Fundamental chemistry, KOKA01 General and Inorganic Chemistry KOK012 or KOKA05 Organic chemistry. KFKA05 Molecular Driving Forces 1: Thermodynamics or FAFA05 Physics - Waves, Thermodynamics and Atomic Physics. KBK011 Biokemi, KBKA05 Technical Biology or TEK295 Biology of the Cell.
The number of participants is limited to: No
The course overlaps following course/s: KOK085

Reading list

Contact and other information

Course coordinator: Professor Ulf Nilsson, ulf.nilsson@chem.lu.se
Course homepage: http://www.chem.lu.se/education/Kemiteknik&Bioteknik/MedChem/MedChem.html