Course syllabus

Cellbiologi
Cell biology

KBK070, 7,5 credits, G2 (First Cycle)

Valid for: 2014/15
Decided by: Education Board C
Date of Decision: 2014-04-14

General Information

Main field: Technology.
Elective Compulsory for: B3
Language of instruction: The course will be given in Swedish

Aim

The aim of the course is to give an understanding of basic molecular mechanisms in a living cell.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

• be able to describe the structure and function of DNA
• be able to describe and evaluate the different steps of the central dogma.
• be able to describe cultivation of mammalian cells in small and large scales.
• be able to describe and explain the structure and function of the immune system.
• be able to describe and explain the central parts of human physiology at a molecular level

Competences and skills
For a passing grade the student must

• be able to prepare and isolate eucaryot DNA.

Judgement and approach
For a passing grade the student must

• be able to make a written report of a central area in cell biology based on individually collected scientific articles.

Contents

Molecular genetics of the cell. The cell nucleus and the organisation of the chromatin. Gene structure, exons and introns. Evolution of the genome. Flow of information in the cell. DNA replication, repair and genetic recombination. RNA and its roles, translation to proteins. Protein sorting and secretion. Cell division, mitosis, control of the cell cycle, meiosis. Functional genomics. Molecular physiology. Cultivation of higher eucaryotic cells.

Examination details

Grading scale: TH
Assessment: Written report of an individual literature task. Written exam. Approved laboratory report is required.

Parts
Code: 0105. Name: Cell Biology, Theory.
Credits: 6. Grading scale: TH. Assessment: Written report of an individual literature task. Written examination. Contents: Molecular genetics of the cell. The cell nucleus and the organisation of the chromatin. Gene structure, exons and introns. Evolution of the genome. Flow of information in the cell. DNA replication, repair and genetic recombination. RNA and its roles, translation to proteins. Protein sorting and secretion. Cell division, mitosis, control of the cell cycle, meiosis. Functional genomics. Molecular physiology. Cultivation of higher eucaryotic cells.
Code: 0205. Name: Cell Biology, Practicals.
Credits: 1,5. Grading scale: UG. Assessment: Approved laboratory report. Contents: Purification of eucaryot DNA

Admission

Admission requirements:

• KBK011 Biochemistry

The number of participants is limited to: No
The course overlaps following course/s: KBK020

Reading list

• Berg, J.M. and Tymoczko, J.L., Stryer, L.: Biochemistry. W.H. Freeman & Co, 2007, ISBN: 0-7167-8724-5 eller 978-1-4292-2936-4.
• Laboratory compendium.

Contact and other information

Course coordinator: Prof Olof Olsson,
Course homepage: http://www.tbiokem.lth.se