Course syllabus

Biokemi
Biochemistry

TEK287, 15 credits, G2 (First Cycle)

Valid for: 2013/14
Decided by: Education Board C
Date of Decision: 2013-04-15

General Information

Elective for: N4-nbm
Language of instruction: The course will be given in Swedish

Aim

Learning outcomes

Knowledge and understanding
For a passing grade the student must

• have a fundamental understanding of how protein structure is determined, and how the structure in turn determines the function of a protein.
• have a fundamental understanding of how enzymes catalyze reactions essential for life.
• have a fundamental understanding of how these reactions are regulated.
• have a fundamental understanding of common catalytical mechanisms.
• have a fundamental understanding of enzyme kinetics, and how these are used to study enzymes.
• have a fundamental understanding of the metabolism of the cell, including glyconeogenesis, glycogen metabolism, fatty-acid metabolism, and the metabolism of proteins and amino acids.
• have a fundamental understanding of the drug development process.
• have a fundamental understanding of the theory behind protein purification and investigation methods, such as electrophoresis, chromatography, centrifuging, spectroscopy, and X-ray crystallography.
• have a fundamental understanding of bioinformatics and its applications.

Competences and skills
For a passing grade the student must

• have achieved skills in practical biochemistry, including protein purification, affinity chromatography, gel electrophoresis, and activity measurements with fluorimetry.
• have achieved skills in experiment planning.
• have achieved skills in analyzing biochemical data and performing enzyme kinetic calculations.
• have achieved skills in searching protein databases and literature databases for bioinformatic information, and in analyzing this information with PDB viewer.
• have achieved skills in conducting a biochemical discussion at a high intellectual level.

Contents

The structure of the cell; structure and function of nucleic acids, proteins and membranes; enzyme catalysis; electron transport and oxidative phosphorylation; photosynthesis; cellular metabolism and its regulation; cell biological methods.

Examination details

Grading scale: TH
Assessment: Written and oral examination.

Admission

Admission requirements:

• KOKA01 General and Inorganic Chemistry
• KOKA05 Organic Chemistry
• TEK295 Biology of the Cell
• TEK015 Human Physiology

The number of participants is limited to: 20
Selection: Credits remaining for the degree.
The course overlaps following course/s: MOB102

Reading list

• Berg, Tymoczko and Stryer: Biochemistry. WH Freeman and Company, 2011, ISBN: 9781429276351.
• Precise reading instructions will be available when the course begins.

Contact and other information

Course coordinator: Cecilia Emanuelsson, Cecilia.Emanuelsson@biochemistry.lu.se
Course coordinator: Henrik Stålbrand, Henrik.Stalbrand@biochemistry.lu.se
Course homepage: http:// http://www.kemi.lu.se/utbildning/grund/moba02/
Further information: The course is given by the Faculty of Science and does not follow the study period structure. The teaching consists of lectures, group exercises and assignments. The course is given in English during the autumn semester and in Swedish during the spring semester.