Course syllabus

Biokemi
Biochemistry

TEK287, 15 credits, G2 (First Cycle)

Valid for: 2012/13
Decided by: Education Board 2
Date of Decision: 2012-04-04

General Information

Elective for: N4-nbm
Language of instruction: The course might be given in English

Aim

Learning outcomes

Knowledge and understanding
For a passing grade the student must

• have a fundamental understanding of how protein structure is determined, and how the structure in turn determines the function of a protein.
• have a fundamental understanding of how enzymes catalyze reactions essential for life.
• have a fundamental understanding of how these reactions are regulated.
• have a fundamental understanding of common catalytical mechanisms.
• have a fundamental understanding of enzyme kinetics, and how these are used to study enzymes.
• have a fundamental understanding of the metabolism of the cell, including glyconeogenesis, glycogen metabolism, fatty-acid metabolism, and the metabolism of proteins and amino acids.
• have a fundamental understanding of the drug development process.
• have a fundamental understanding of the theory behind protein purification and investigation methods, such as electrophoresis, chromatography, centrifuging, spectroscopy, and X-ray crystallography.
• have a fundamental understanding of bioinformatics and its applications.

Competences and skills
For a passing grade the student must

• have achieved skills in practical biochemistry, including protein purification, affinity chromatography, gel electrophoresis, and activity measurements with fluorimetry.
• have achieved skills in experiment planning.
• have achieved skills in analyzing biochemical data and performing enzyme kinetic calculations.
• have achieved skills in searching protein databases and literature databases for bioinformatic information, and in analyzing this information with PDB viewer.
• have achieved skills in conducting a biochemical discussion at a high intellectual level.

Contents

The structure of the cell; structure and function of nucleic acids, proteins and membranes; enzyme catalysis; electron transport and oxidative phosphorylation; photosynthesis; cellular metabolism and its regulation; cell biological methods.

Examination details

Grading scale: TH
Assessment: Written and oral examination.

Admission

Admission requirements:

• TEK285 Chemistry – from General Chemistry to the Molecules of Life, TEK295 Biology of the Cell, and TEK015 Human Physiology

The number of participants is limited to: 20
Selection: Credits remaining for the degree.
The course overlaps following course/s: MOB102

Reading list

• Berg, Tymoczko and Stryer: Biochemistry. WH Freeman and Company 2007. ISBN: 0-7167-8724-5.
• Precise reading instructions will be available.

Contact and other information

Course coordinator: Cecilia Emanuelsson, Cecilia.Emanuelsson@biochemistry.lu.se
Course homepage: http://www.mps.lu.se/
Further information: The course is given by the Faculty of Science and does not follow the study period structure. The teaching consists of lectures, group exercises and assignments.