Course syllabus

Magnetisk resonans - spektroskopi och avbildning
Magnetic Resonance - Spectroscopy and Imaging

KFKN01, 7,5 credits, A (Second Cycle)

Valid for: 2012/13
Decided by: Education Board 2
Date of Decision: 2012-04-04

General Information

Elective for: B4-mb, K4-m, N5-m
Language of instruction: The course might be given in English

Aim

The aim of the course is for the student to learn basic knowledge about Nuclear Magnetic Resonance (NMR) and its applications in the studies of structure and dynamics in macromolecular and colloidal systems. The course also addresses imaging techniques and methods for the studies of solid materials.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

Competences and skills
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Contents

Lectures: The course begins with basic theory for Nuclear Magnetic Resonance, including an introduction to quantum mechanics. Then follow lectures on chemical shift, nuclear spin interactions, spin dynamics, chemical exchange, relaxation, multi-dimensional applications (including structure determination of macromolecules) and methods for imaging and the study of self-diffusion. The last part of the course is a possibility for each student to make a deeper descent into a subject that he or she finds interesting and relevant. A visit to the MR department at the Lund University Hospital might be offered.

Practicals: An introduction to the data treatment in NMR (including topics like the Fourier transform and artefacts) is followed by practicals covering chemical exchange, relaxation, imaging and self diffusion. An extra practical might be offered as a part of the student’s intensifying task. That practical might cover, for example, structure determination, solid state NMR or molecular dynamics.

Examination details

Grading scale: TH
Assessment: For a passing grade (3, 4 or 5), the student must pass a written examination, practicals, home assignments and an intensifying task. The final grade is given by the overall result of all mandatory tasks.

Admission

Required prior knowledge: Mathematics (analysis and linear algebra) and physical chemistry (thermodynamics, intermolecular interactions).
The number of participants is limited to: No
The course might be cancelled: If the number of applicants is less than 5.
The course overlaps following course/s: KFK095

Reading list

Contact and other information

Course coordinator: Mikael Akke, mikael.akke@bpc.lu.se
Course coordinator: Kristofer Modig, kristofer.modig@bpc.lu.se
Course homepage: http://www.bpc.lu.se
Further information: The course is also given as KEMM17 at the faculty of Science and is taught as a collaboration between the divisions of Biophysical Chemistry and Physical Chemistry. The two department share many years of experience with a multitude of different applications of the technique.