Syllabus academic year 2011/2012
(Created 2011-09-01.)
Credits: 7,5. Grading scale: TH. Cycle: A (Second Cycle). Main field: Technology. Language of instruction: The course will be given in English on demand. KOK090 overlaps following cours/es: KOK020 and KOK021. Optional for: B4l, K4l, K4m. Course coordinator: Univ.lecturer Kenneth Wärnmark,, Bioorganic Chemistry. Prerequisites: KOK012 Organic chemistry, basic course. Assessment: To pass the course you need to pass a written exam. Home page:

The aim of the course is to give advanced knowledge in synthetic organic chemistry and knowledge in physical organic chemistry.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

The course deals primary with organic chemical reactions for the creation of C-C bonds emphasising enolate chemistry but also using pericyclic reactions and radical chemistry. The course also gives advanced knowledge in oxidation and reduction reactions in organic chemistry. The emphasis is on the different chemo-, regio- and diastereoselectivity of the different reaction types. Fundamental retrosynthetic analysis of target molecules is used as means to design multistep synthesis. The course is focused on applying a mechanistic approach to understand the outcome of chemical reactions and to emphasise this, the reactions are analyzed using basic frontier orbital analysis. A large part of the course treats methods to elucidate mechanisms of reactions such as linear free energy relationships and the primary isotope effect.

An important aspect of the course is to orally present organic reactions to other students. The role of organic chemistry and in material science will be presented.

Clayden, J, Greeves, N, Warren, S, Wothers, P: Organic Chemistry. Oxford University Press 2001. ISBN 0-19-850346-6.