Syllabus academic year 2011/2012
(Created 2011-09-01.)
MEDICINAL CHEMISTRYKOK085
Credits: 7,5. Grading scale: TH. Cycle: G2 (First Cycle). Main field: Technology. Language of instruction: The course will be given in English on demand. Compulsory for: B4l, K4l. Optional for: N4nbm. Course coordinator: Professor Ulf Nilsson, ulf.nilsson@organic.lu.se, Bioorganic Chemistry. Recommended prerequisits: KOK012 Organic chemistry or a corresponding course. The course might be cancelled if the number of applicants is less than 5. Assessment: Written assessment. Home page: http://www.organic.lu.se/Education/Kemiteknik&Bioteknik/MedChem/MedChem.html.

Aim
The aim of the course is to give basic knowledge in and broad understanding of medicinal chemistry and pharmacological principles from a molecular perspective.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Contents
The course discusses general pharmacological principles, drug development and presents various classes of drugs, their effects, their use, and chemical structures. Important parts of medicinal chemistry, such as drugs of the nerve system, hormone drugs, drugs affecting the heart, respiratory drugs, anaesthetics, sedative drugs, antivirals, antibiotics, and cancer drugs. Methods for searching novel drug candidates (drug development), development of computer models for prediction of various pharmacological properties, and structure-activity relationships are discussed.

Literature
Graham L P: An introduction to Medicinal Chemistry. Oxford University Press, 4th edition, 2009. ISBN: 978-0-19-923447-9.