Syllabus academic year 2011/2012
(Created 2011-09-01.)
Credits: 7,5. Grading scale: TH. Cycle: A (Second Cycle). Main field: Technology. Language of instruction: The course might be given in English. KFKN01 overlaps following cours/es: KFK095. Optional for: B4mb, K4m, N5m. Course coordinator: Mikael Akke, and Kristofer Modig,, Biophysicalic Chemistry. Recommended prerequisits: Mathematics (analysis and linear algebra) and physical chemistry (thermodynamics, intermolecular interactions). The course might be cancelled if the number of applicants is less than 5. Assessment: For a passing grade (3, 4 or 5), the student must pass a written examination, practicals, home assignments and an intensifying task. The final grade is given by the overall result of all mandatory tasks. Further information: The course is also given as KEMM17 at the faculty of Science and is taught as a collaboration between the divisions of Biophysical Chemistry and Physical Chemistry. The two department share many years of experience with a multitude of different applications of the technique. Home page:

The aim of the course is for the student to learn basic knowledge about Nuclear Magnetic Resonance (NMR) and its applications in the studies of structure and dynamics in macromolecular and colloidal systems. The course also addresses imaging techniques and methods for the studies of solid materials.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Lectures: The course begins with basic theory for Nuclear Magnetic Resonance, including an introduction to quantum mechanics. Then follow lectures on chemical shift, nuclear spin interactions, spin dynamics, chemical exchange, relaxation, multi-dimensional applications (including structure determination of macromolecules) and methods for imaging and the study of self-diffusion. The last part of the course is a possibility for each student to make a deeper descent into a subject that he or she finds interesting and relevant. A visit to the MR department at the Lund University Hospital might be offered.

Practicals: An introduction to the data treatment in NMR (including topics like the Fourier transform and artefacts) is followed by practicals covering chemical exchange, relaxation, imaging and self diffusion. An extra practical might be offered as a part of the student’s intensifying task. That practical might cover, for example, structure determination, solid state NMR or molecular dynamics.

Keeler, J: Understanding NMR Spectroscopy. Wiley 2005. ISBN: 0-470-01787-2.
Instructions for practicals.
Other literature (mostly scientific articles) are handed out during the course.