Syllabus academic year 2010/2011
(Created 2010-07-25.)
BIOCHEMICAL REACTION ENGINEERINGKTE071
Credits: 7,5. Grading scale: TH. Cycle: A (Second Cycle). Main field: Technology. Language of instruction: The course will be given in English on demand. Compulsory for: B4pt. Alternative for: MBIO2. Optional for: K4p, W4p. Course coordinator: Professor Gunnar Lidén, Gunnar.Liden@chemeng.lth.se, Chemical Engineering. Recommended prerequisits: KBK011, FMA420, KET045 or KTE170. Assessment: Written examination. Assignments. Home page: http://www.chemeng.lth.se/kte071/.

Aim
The aim of the course is to provide the student with understanding and skills to enable them to analyse a biotechnical process in a quantitative fashion. The student should be able to make the quantitative analysis on the cellular as well as the reactor level. This will provide the basis for the identification of critical factors in the design and scale-up of processes in biotechnology.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Contents
The course treats processes in biotechnology in a quantitative fashion on both the cellular and the reactor level. The following topics are covered: Metabolic reactions, stoichiometry, the C-mol concept, degree of reduction, thermodynamics in microbial systems, modelling of metabolic networks, reaction kinetics, design of biotechnical processes, mass transfer, and scale-up of biotechnical processes.

The course consists of lectures, tutorials and assignments.

A significant part of the course is allocated to quantitative problem solving. The problem solving includes both short examples and somewhat more complex problems which are dealt with by computer simulations. The written examination is focused on problem solving.

Literature
Nielsen J, Villadsen, J och Lidén, G: Bioreaction Engineering Principles, 2nd ed. Kluwer Academic/Plenum Press 2003. ISBN: 0-306-47349-6.