Syllabus academic year 2010/2011
(Created 2010-07-25.)
MOLECULAR CELL BIOLOGYKMB050
Credits: 15. Grading scale: TH. Cycle: G1 (First Cycle). Main field: Technology. Language of instruction: The course will be given in English. Compulsory for: W2. Course coordinator: Professor Peter Rådström, Docent Lei Ye, Professor Ulf Nilsson, Peter.Radstrom@tmb.lth.se, Applied Microbiology. Assessment: Written examination and written reports. Extra credits can be given for a voluntary oral presentation based on a literature study. Home page: http://www.tmb.lth.se.

Aim
To provide basic, theoretical and practical, knowledge about the reactivity of chemical compounds and toxicity as well as to highlight the structure and function of living cells, in particular the microorganisms.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Contents
The course introduces the student to the fascinating world of living cells, in particular bacteria, their genetics and physiology. The course covers enzymatic catalysis, genome of cells, cellular transport mechanisms and techniques to detect, quantify, identify and cultivate different types of microorganisms. In addition, cellular energy metabolism is covered in order to give a deeper understanding of biogeochemical cycles. In connection to energy metabolism aspects of respiration and photosynthesis are exposed.

The laboratory exercises illustrate theoretical aspects of the course such as the reactivity of chemical compounds and toxicity, purification and characterisation of enzymes, and how microorganisms may adapt to new environments through genetic exchange. The diversity of microorganisms and functionality are illustrated by studying the morphology, physiology, and growth behaviour. The genetic expression and regulation is exemplified by determining the physiological adaptation of bacteria under different cultivation conditions. The influences of cytotoxic and antimicrobial compounds are studied on eukaryotic cells as well as on bacteria.

Literature
Prescott, L.M., Harley, J.P. and Klein, D.A., Microbiology, Seventh Edition, McGraw-Hill, 2007. ISBN 978-0-07-110231-5.
Compendium in Biochemistry.
Lecture material.
Laboratory manual.