Syllabus academic year 2009/2010
(Created 2009-08-11.)
MEDICINAL CHEMISTRYKOK085

Higher education credits: 7,5. Grading scale: TH. Level: G2 (First level). Language of instruction: The course will be given in English on demand. Compulsory for: B4l, K4l. Optional for: N4. Course coordinator: Univ. lecturer Ulf Nilsson, ulf.nilsson@organic.lu.se, Bioorganisk kemi. The course might be cancelled if the numer of applicants is less than 5. Assessment: For a passing grade the student must pass a written final examination. Home page: http://www.organic.lu.se/Education/Kemiteknik&Bioteknik/MedChem/MedChem.html.

Aim
The aim of the course is to give basic knowledge in and broad understanding of medicinal chemistry and pharmacological principles from a molecular perspective.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Contents
The course discusses general pharmacological principles and presents various classes of drugs, their effects, their use, and chemical structures. Important parts of medicinal chemistry, such as drugs of the nerve system, hormone drugs, drugs affecting the heart, respiratory drugs, anaesthetics, sedative drugs, antivirals, antibiotics, and cancer drugs. Methods for searching novel drug candidates (drug development), development of computer models for prediction of various pharmacological properties, and structure-activity relationships are discussed.

Literature
Graham L P: An introduction to Medicinal Chemistry. Oxford University Press, 3rd edition, 2005. ISBN: 0-19-927500-9.