Syllabus academic year 2008/2009
Higher education credits: 15.
Grading scale: UV.
Language of instruction: The course might be given in English.
Optional for: N4, N4nbm.
Course coordinator: Klas Flärdh, firstname.lastname@example.org, Inst f cell- och organismbiologi.
Prerequisites: TEK285 Chemistry from General Chemistry to the Molecules of Life, TEK295 Biology of the Cell, TEK015 Human Physiology, TEK287 Biochemistry and TEK012 Genetics and Microbiology.
The number of participants is limited to 5
Selection criteria: Credits remaining for the degree.
Assessment: Teaching consists of lectures, practicals and seminars. One extensive practical project work is included. All participants give an oral presentation of their project work. Study visits are made at laboratories and industries related to microbiology. Practicals and seminars, and the course elements associated with these are compulsory. Examination takes the form of written tests at the end of the course. Students who fail the ordinary tests will have an opportunity to take another test in close proximity to the ordinary test. To be awarded a Pass on the whole course the students shall have passed the tests, have acceptable practical reports and to have participated in all compulsory course elements. The final grade for the course is determined by the result of the written examination.
Home page: http://www.cob.lu.se.
The aim of the course is to provide knowledge for advanced studies, work and research especially within chemical-biological-biochemical areas.
Knowledge and understanding
For a passing grade the student must
- be able to give an account of a modern view of prokaryotic phylogeny and diversity
- be able to give an account of the structure and function of the prokaryotic cell, and compare the characteristic features of bacteria and archaea
- be able to give an account of the main types of energy metabolism among microorganisms, their roles in biogeochemical cycles, and how they are coupled to the provision of building blocks for anabolic processes
- be able to give an account of kinetic and physiological aspects of bacterial growth and cell cycles
- be able to give an account of global regulatory systems and give examples of cellular differentiation among bacteria
- be able to give an account of molecular methods for analysis and characterisation of natural microbial communities
- be able to give an account of the main types of antibiotics, their modes of action, and the emergence of antibiotic resistance
- be able to give an account of the main types of bacterial toxins and their modes of action
- be aware of the importance and and utility of microorganisms in medicine, food and biotechnological industry, and plant cultivation
Skills and abilities
For a passing grade the student must
- have been trained in microbiological methodology and experimental work
- together with another student have independently planned, realised, and presented an extensive project about the enrichment, isolation, and characterisation of a specific group of bacteria
- have been trained in oral presentation of a scientific project
Phylogeny, classification and diversity of prokaryotic microorganisms.
Structure and function of prokaryotic cells. Transport of small molecules over membranes. Translocation of proteins over membranes.
Oxidation of organic compounds. Metabolism of carbon and nitrogen. Aerobic och anaerobic energy metabolism. Chemolithotrofy. Bacterial photosynthesis. Synthesis of building blocks for macromolecules.
Microbial growth. Bacterial cell cycles and cellular differentiation.
Global regulatory systems in bacteria. Motility and chemotaxis. Communication between cells.
Introduction to microbial ecology. Biogeochemical cycles.
Introduction to medical bacteriology. Toxins. Antibiotics and antibiotic resistance.
Overview of applied microbiology (food, industrial microbiology, interactions between plants and bacteria).
Basic microbiological and aseptic techniques, media and cultivation. Enrichment and isolation.
According to a list established by the department, available at least five weeks before the start of the course, see the web-page for Undergraduate Studies in Biology.