Syllabus academic year 2007/2008
CELL BIOLOGYKBK070

Higher education credits: 7,5. Grading scale: TH. Level: G2 (First level). Language of instruction: The course will be given in Swedish. KBK070 overlap following cours/es: KBK020 och KBK020. Alternative for: B3. Optional for: B4mb. Course coordinator: Professor Leif Bülow, leif.bulow@tbiokem.lth.se, Tillämpad biokemi. Prerequisites: KBK011 Biokemi. Assessment: Written report of an individual literature task. Written exam. Approved laboratory report is required. Parts: 2. Home page: http://www.tbiokem.lth.se.

Aim
The aim of the course is to give an understanding of basic molecular mechanisms in a living cell.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Contents
Molecular genetics of the cell. The cell nucleus and the organisation of the chromatin. Gene structure, exons and introns. Evolution of the genome. Flow of information in the cell. DNA replication, repair and genetic recombination. RNA and its roles, translation to proteins. Protein sorting and secretion. Cell division, mitosis, control of the cell cycle, meiosis. Functional genomics. Molecular physiology. Cultivation of higher eucaryotic cells.

Literature
Berg, J.M. and Tymoczko, J.L., Stryer, L.: Biochemistry, W.H. Freeman & Co, San Francisco 2007. ISBN: 0-7167-8724-5
Laboratory compendium

Parts

Code: 0105. Name: Cell Biology, Theory.
Higher education credits: 6. Grading scale: TH. Assessment: Written report of an individual literature task. Written examination. Contents: Molecular genetics of the cell. The cell nucleus and the organisation of the chromatin. Gene structure, exons and introns. Evolution of the genome. Flow of information in the cell. DNA replication, repair and genetic recombination. RNA and its roles, translation to proteins. Protein sorting and secretion. Cell division, mitosis, control of the cell cycle, meiosis. Functional genomics. Molecular physiology. Cultivation of higher eucaryotic cells.

Code: 0205. Name: Cell Biology, Practicals.
Higher education credits: 1,5. Grading scale: UG. Assessment: Approved laboratory report. Contents: Purification of eucaryot DNA.