Syllabus academic year 2007/2008

Higher education credits: 7,5. Grading scale: TH. Level: A (Second level). Language of instruction: The course will be given in English on demand. Alternative for: MBIO1. Optional for: B4mb, B4pt. Course coordinator: Professor Leif Bülow,, Tillämpad biokemi. Prerequisites: KBK041. Assessment: Written and problem-oriented home exam. Oral group presentation of material taken from the scientific literature. Approved reports from exercises and practicals are also required. Home page:

The aim of the course is to give a deeper understanding of protein structure and function.

Knowledge and understanding
For a passing grade the student must

Skills and abilities
For a passing grade the student must

Judgement and approach
For a passing grade the student must

Random and site-directed mutations of proteins using genetic methods are described. Combinatorial methods using biological and chemical approaches are treated. The course also includes a practical task where the student independently design a modified protein.

Brown, T.A.: Gene Cloning and DNA Analysis. Blackwell Publishing 2006. ISBN: 1405111216.
Brändén, C-I., Tooze, J.: Introduction to Protein Structure. Garland Publishing Inc. 1999. ISBN: 0-8153-2305-0.
Laboratory compendium, distributed during the course
Computer exercise compendium, distributed during the course